Originally Posted by
olivia0703
I wish he'd just give me a truckload of benzos
Benzodiazepines might give you temporary relief, Olivia, but they actually worsen anxiety disorders (also depression) and when taken with ADs they can block their mode of action so reducing their effectiveness. See:
Boldrini M, Butt TH, Santiago AN, et al. (2014)
Benzodiazepines and the potential trophic effect of antidepressants on dentate gyrus cells in mood disorders.
Int J Neuropsychopharmacol. Dec;17(12):1923-33 (
Abstract |
Full text)
Sun Y, Evans J, Russell B, et al (2013)
A benzodiazepine impairs the neurogenic and behavioural effects of fluoxetine in a rodent model of chronic stress.
Neuropharmacology. Sep;72:20-8 (
Abstract)
Song J, Zhong C, Bonaguidi MA, et al (2012)
Neuronal circuitry mechanism regulating adult quiescent neural stem-cell fate decision.
Nature. Sep 6;489(7414):150-4 (
Article |
Study full text)
Wu X, Castren E. (2009)
Co-treatment with diazepam prevents the effects of fluoxetine on the proliferation and survival of hippocampal dentate granule cells.
Biol Psychiatry. Jul 1;66(1):5-8 (
Abstract)
See also: the 'Ugly' part of
Benzodiazepines: The Good, The Bad, and the Ugly.
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